At Gynera, we have developed an unique program, specifically designed for couples: Gynera For BOTH of Us, where both partners are evaluated through an integrated approach by a multidisciplinary team consisting of an IVF specialist, urologist/andrologist, geneticist, and embryologist, complemented, when needed, by personalized lifestyle recommendations and coaching.
Couple infertility is not only about female fertility. Today, we know that the male factor is involved in nearly half of infertility cases, which is why male fertility deserves the same level of attention and medical rigor.
For almost 20 years, Gynera has integrated male fertility into the complete fertility diagnosis of the couple from the very beginning, providing both partners with a thorough and personalized evaluation. This approach allows us to build more precise treatment strategies and improve success rates by combining medical expertise, targeted interventions when needed, lifestyle optimization, and the support of a multidisciplinary team.
Through the Gynera For BOTH of Us program, we take this philosophy even further by integrating AI Success Predictor — an artificial intelligence-based tool that helps estimate ovarian stimulation response, probability of success, and define an optimal, personalized IVF strategy for each couple.
Gynera is the only IVF clinic in Romania that offers access to this advanced decision-support tool, helping patients gain a clearer, more realistic understanding of their chances of success before starting treatment.
This program is especially dedicated to couples who:
- have been trying to conceive for more than one year without success;
- have experienced IVF failures, poor-quality embryos, or pregnancy losses;
- face unexplained infertility;
- have hormonal conditions or a history of urological disorders;
- are over 40 and planning to have children;
- have experienced recurrent infections or sexually transmitted diseases;
- work in high-risk environments involving excessive heat, radiation, chemicals, or intense physical stress (drivers, sailors, pilots, professional athletes, etc.).
Because male fertility evaluation is much more than a simple semen analysis. It involves understanding sperm genetic quality, sperm DNA integrity, lifestyle impact, and how all these factors influence embryo development and the real chances of achieving pregnancy.
Male fertility is an essential factor that is often overlooked. Many men only evaluate their fertility after difficulties in achieving pregnancy arise.
The reality is:
- male infertility is involved in approximately 40–50% of infertility cases;
- in many situations, there are no visible symptoms;
- early diagnosis can completely change the treatment journey and available options.
The good news is that, in many cases, male fertility can be improved or treated, especially when evaluation is performed correctly and at the right time.
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This exceptionally rare and challenging case brings hope to thousands of men facing male-factor infertility, demonstrating that even in the most difficult circumstances, the dream of having a biological child may still become a reality.
The highest number of IVF babies in Romania (during 2007–2025)
In 2025, 2 out of 3 patients under the age of 40 achieved a positive pregnancy test following IVF procedures at Gynera (67%)*(the rate refers to positive BHCG tests per procedure in patients ≤40 years old during 2025.)
At Gynera, we use advanced sperm diagnostic and selection technologies, AI-assisted embryology, and personalized protocols for every couple. From specialized urology consultations and Male Infertility Board reviews, to MACS, ZYMOT, ICSI/PICSI, EmbryoScope®, and iDAScore, every step is designed for greater precision and evidence-based medical decisions.
These are subtle aspects that cannot always be identified in a single test result, yet they can make a significant difference in your journey toward pregnancy.
That is why, at Gynera, we view male fertility as an essential part of a complex ecosystem: the couple.
A complete evaluation comes from correlating all information within the context of your real story.
nearly 20 years of dedicated expertise in male infertility
a multidisciplinary approach involving IVF specialists, andrology-trained urologists, embryologists/andrologists
a state-of-the-art embryology laboratory built to international standards
integration of reproductive genetics into the complete fertility evaluation
personalized protocols tailored to each couple, not standard approaches
advanced sperm selection technologies (MACS, ZYMOT), supporting better-informed medical decisions
AI IVF Clarity, an artificial intelligence-based tool that helps estimate ovarian stimulation response, probability of success, and define an optimal IVF strategy
Here, fertility evaluation means programs specifically designed for both partners.
Beyond our extensive expertise in couple infertility, at Gynera you benefit from:
At Gynera, every case is evaluated in an integrated way by a multidisciplinary team working together toward the same goal: helping you fulfill your dream of becoming parents.
The IVF specialist builds the overall picture. They integrate both partners’ results and define a treatment strategy adapted to your medical history and reproductive goals.
Investigates the male fertility component in depth, identifying treatable causes ranging from varicocele and infections to hormonal imbalances or factors affecting sperm quality. He is the specialist dedicated to male reproductive health.
Looks beyond numbers and standard parameters. Evaluates the real reproductive potential of sperm cells and selects the most appropriate sperm selection methods using advanced technologies that may directly influence the final outcome.
Completes the evaluation by identifying genetic causes that may affect fertility, embryo quality, or pregnancy evolution. From sperm DNA fragmentation and chromosomal abnormalities to genetic conditions that may remain “invisible” in standard investigations, the geneticist contributes to establishing a more precise diagnosis.
Male fertility, an essential factor, is often overlooked. Many men only evaluate their fertility after difficulties in achieving pregnancy appear.
The reality is:
The good news: in many cases, male fertility can be improved or treated, especially when evaluation is accurate and performed at the right time.
when pregnancy is delayed
when there is a history of infertility in the couple
after IVF failures
when you want to understand your fertility early
when risk factors are present (smoking, stress, unhealthy lifestyle, poor diet, etc.)
Fertility is not only about “if”, but also about when and how.
Magnetic-Activated Cell Sorting (MACS) is an advanced technology used in the IVF laboratory to select healthy sperm cells with intact DNA.
How does it work?
- damaged sperm cells are marked with magnetic particles
- they are retained inside a magnetic column
- only healthy sperm cells are selected
The result is a biologically more precise selection compared to standard methods.
Who can benefit from MACS?
MACS may make a difference in cases such as:
- high sperm DNA fragmentation (DFI >30%)
- unexplained infertility
- abnormal sperm morphology
- varicocele
- repeated IVF / ICSI failures
What are the benefits?
- increases fertilization chances
- improves embryo quality
- reduces miscarriage risk
A technology designed to optimize not only the procedure, but the final outcome.
Male fertility testing may identify:
- poor sperm quality
- increased sperm DNA fragmentation
- genetic factors
- lifestyle impact (smoking, nutrition, stress)
- medical causes (such as varicocele or infections)
Essential information for understanding why pregnancy is delayed.
After interpreting the investigation results, every case is approached individually through a unique program specifically designed by the Gynera team.
Because every couple is different, and fertility has no standard solutions.
Depending on the results, the physician may recommend:
- personalized lifestyle modifications
- medical treatment when indicated
- assisted reproductive procedures (IVF / ICSI / PICSI)
- advanced sperm selection techniques to improve success rates
The goal is clear: maximizing the chances of achieving a healthy pregnancy.
At Gynera, for over 20 years, we have evaluated and treated male infertility with the help of urologists specialized in andrology and male reproductive medicine, integrating the male factor from the very beginning into the couple’s complete fertility diagnosis. We know that male fertility means more than a semen analysis and that factors such as sperm DNA integrity, medical history, or embryo quality may directly influence pregnancy chances.
Today, through the Gynera For BOTH of Us program, we further advance this approach by integrating AI IVF Clarity — an artificial intelligence-based tool that helps estimate ovarian stimulation response, probability of success, and define an optimal and personalized IVF strategy for every couple.
A semen analysis is a basic test used to evaluate sperm quality by assessing parameters such as sperm count, motility (movement), and morphology (shape). In most cases, it is the first step in evaluating male fertility.
Not always.
A semen analysis provides important information, but it does not capture all aspects of male fertility. Issues such as sperm DNA fragmentation, oxidative stress, or genetic abnormalities may exist even when standard semen parameters appear normal
Male infertility is involved in approximately 40–50% of infertility cases, either as the main factor or alongside a female factor. Despite this, it is often underdiagnosed or investigated too late.
Sperm DNA fragmentation is an indicator of the genetic quality of sperm cells. High levels are associated with lower fertilization rates, poorer embryo quality, and an increased risk of miscarriage, even when the semen analysis appears normal.
MACS (Magnetic Activated Cell Sorting) is an advanced sperm selection technology used in IVF procedures that allows the isolation of viable sperm cells with intact DNA, reducing the risk of using sperm with genetic damage.
Yes, in many cases.
Depending on the cause, male fertility may be improved or treated through:
Male fertility testing is recommended:
No.
Infertility is not related to sexual function. A man may have normal erections and ejaculation, but poor sperm quality.
Yes, significantly.
Smoking, alcohol consumption, chronic stress, poor diet, and sedentary lifestyle can affect sperm quality and DNA integrity, influencing not only fertility but also the future child’s health.
Yes.
After the age of 40, the risk of sperm DNA fragmentation, genetic abnormalities, and miscarriage increases, even if semen analysis parameters appear normal.
ICSI may facilitate fertilization, but it does not repair damaged sperm DNA. That is why it is essential for the male factor to be properly investigated and treated, not simply bypassed through laboratory techniques.
TESE (testicular sperm extraction) is a modern procedure that allows sperm retrieval directly from the testicle. It is useful in severe cases, including situations where sperm cells are absent from the ejaculate.
Yes. Some of the most important fertility issues involve sperm DNA integrity, genetic factors, or sperm functionality, which cannot be identified through standard tests and require advanced investigations.
Now you can also book online consultations!